Abstract: In order to solve the problem of serious instability and failure after excavation and support of track main roadway in the east wing of Hongyang Coal Mine, field investigation, numerical simulation, drilling peeping, mine pressure monitoring and other means are adopted to summarize and analyze the causes of instability and failure according to the failure characteristics and geological conditions of roadway surrounding rock, and the surrounding rock control concept is proposed. The integrated bolt-grouting and surrounding rock reinforcement is realized, and the feasibility and effectiveness of support measures are simulated by FLAC^3D software. The surface deformation of roadway and the development depth of plastic zone of surrounding rock are significantly lower under the conditions of the new combined bolt support than that of the conventional prestressed bolt, and the reasonable length of the bolt is determined to be 2.5-3.0 m. In the application stage, drilling coring and comprehensive ore pressure monitoring are carried out. The research shows that: Under the condition of passive support of the original shelf, the depth of loose ring development reaches 2.5～3.0 m. After reinforced by combined anchor rod and hollow grouting cable, high-strength inorganic grouting can effectively fill the cracks in weak fractured rock mass. The uniaxial compressive strength of typical rock samples after grouting exceeds 30 MPa, indicating that the integrity and strength of rock mass have been effectively improved. The subsidence of the roadway roof is about 57 mm, the inward movement of the left side and the right side is 22 mm and 29 mm respectively, and the heave of the floor is 38 mm. The surface deformation of the roadway is small, and the combined anchor rod has good working performance and good application effect. The supporting effect and advantages of the new full-length prestressed anchor injection support are verified.