Abstract: In order to reduce the over-head support dust, based on the numerical simulation results of the discrete particle model of Computational Fluid Dynamics (CFD) on the dust diffusion law under the action of the dust collector, and combined with experimental measurements and field tests, a negative-pressure spray dust collector for the dust source of over-head support under the environment of comprehensive mining has been developed. The simulation results show that: the hydraulic support formed a high concentration dust belt with concentration as high as 1000 mg/m³ near the sidewalk at 0～9 m from the windward face of the hydraulic support, and gradually spread to 0～36 m; after adopting the negative-pressure spray dust collector, the concentration of the dust belt in the leeward face of the hydraulic support decreased to less than 300 mg/m³, and the spreading range was narrowed down to the leeward side of the coal miner at 0～5 m; the dust belt near the sidewalk also changed to a low-pressure dust belt. The dust belt pattern near the sidewalk also changed to a low concentration dust belt. After the indoor test, the ultrasonic atomizing nozzle was selected as the final nozzle, and the negative pressure spray collector equipped with this nozzle was used under the same condition of water and gas pressure of 0.4 MPa, with an effective range of 5.03 m and an atomization angle of 71°. The developed negative-pressure spray collector was applied to the 5110 comprehensive mining environment of Tashan coal mine, and it was found that it could effectively reduce the dust concentration of the propelling stent close to the working area of the walkway, and the average total dust reduction rate and respiratory dust reduction rate reached 81.5% and 79.1%, respectively, confirming that the device has good dust reduction effect.